Autoimmune Diseases

Autoimmune Diseases
Autoimmune disease is a disease in which the immune system mistakenly identifies a foreign object is formed, in which the cells, tissues or organs of the human body is regarded as a foreign body so ravaged by antibodies. So the presence of autoimmune disease does not affect the increase in the body's defenses against a disease, but rather the result of the body's immune damage formed. ( NIH , 1998; Schaechter et al., 1993: Salyers and Whitt, 1994: Pelczar et al. 1986: Madigan et al. 1997). 
Is Contagious ?
Has not been proved that this autoimmune disease is contagious. Autoimmune disease does not spread to other individuals as well as infectious diseases. This disease is not as AIDS as well as cancer is not. Individuals with autoimmune disease genes have a contribution to autoimmune disease transmission. Certain diseases such as psoriasis can occur among some members of the family ( NIH, 1998) .
Autoimmune Disease ( Psoriasis )
There are several autoimmune diseases and each can have an impact on the body with a variety of models, for example ; autoimmune reaction takes place affects the brain in cases of multiple sclerosis attacks the gastrointestinal tract and in the case of Crohn 's disease. In the case of other autoimmune diseases , such as lupus erythematosus ( SLE ), affects the tissue and organs which varies between individuals with the same disease-causing. A person with lupus may affects the skin and joints while the other individual cases of lupus affect the skin, kidneys and lungs. In the end the damage to tissues caused by the immune system as it will permanently damage the pancreas cells that produce insulin in diabetes mellitus type I.
Is Main Cause Autoimmune Disease ?
Genetics : It has been shown in humans that genes of major histocompatibility complex ( MHC ) is associated with a specific incidence of autoimmune disease. MHC genes exist in all vertebrates, these genes mark the 2 main categories of molecules that form part of the cell membrane and the entire membrane ( Schaechter et al. , 1993: Henderson et al. , 1999). In particular, these genes have a role in selecting antigens that can be recognized by T-cells. A descendant of dogs beardies analysis showed that hypoadrenocorticism affect the nature of the resulting offspring. This incident caused by an autosomal recessive gene that penetration is not complete.
The researchers hope to identify the gene or genes at one or more loci that have a relationship with hypoadrenocorticism. Pedigree analysis on a large population of Old English Sheepdogs and other breeds in smaller populations, showed that almost all autoimmune cases occurred in animals that have blood line. However, these data also explained that the dogs were in the lineage are not always suffer from an autoimmune disease in which the majority under normal conditions , healthy although some suffer from sub clinical autoimmune disease. The conclusion that can be drawn from the above cases that ; seems dogs have genetic tendency to suffer from autoimmune diseases ( Aronson, 1999).
Other facts show that specific genes or groups of genes as a family predisposition to psoriasis. In addition, individual members of a family with autoimmune disease may play a role in shaping the genetic abnormality that drives the incidence of autoimmune disease autoimmune disease, although probably lower in other autoimmune diseases. For example: one parent suffers from lupus, the possible offspring suffering from dermatomyositis and probably other breeds Rheumatoid arthritis sufferers ( NIH , 1998 ).
Autoimmune Diseases ( rheumatoid - arthritis )
Some autoimmune diseases are known to occur and more is due to the triggering factors such as viral infections. Sunlight not only acts as a trigger for lupus incident but even sunlight can worsen the condition of people with lupus. It is important to realize that these factors can be avoided by susceptible individuals in order to prevent or minimize the amount of damage inflicted by the immune penyakitauto patients. Other factors such as chronic stress, hormonal and pregnancy, yet little known effects on the immune system and autoimmune disease ( Aronson , 1999)
How Autoimmune Disease Mechanisms Genesis ?
If the body is faced with something unfamiliar, the body requires a form of resistance against the immune response to these substances in an effort to protect itself from potential conditions that cause disease. To it effectively will require the ability to recognize themselves in order to give a response to foreign conditions or not himself. Autoimmune diseases occur on a failure to recognize some part of him ( NIH, 1998).
There are 80 groups of serious human autoimmune disease which give an indication of chronic pain that strikes in almost all parts of the human body. The symptoms include disorders caused nervous , gastrointestinal , endocrine system , skin and other connective tissues, eyes, blood, and blood vessel. At the diseases mentioned above , is the main problem of the immune system disorder that caused the wrong direction so that should affect multiple organ protects. 
How to Diagnose Autoimmune Disease ?
Diagnosis is based on symptoms of autoimmune diseases acquired through observation of individual physical condition and results of laboratory tests . Early diagnosis of autoimmune disease is very difficult to do. Some of the symptoms of autoimmune disease, such as lethargy, is not specific. Laboratory tests may be helpful , but often not sufficient in confirming a diagnostic. If an individual suffers from a kind of joint pain symptoms and laboratory results positive but non-specific, then the patient will be diagnose by name confused ( undifferentiated ) as initial or not distinguishable as connective tissue disease (connective tissue disease) ( NIH , 1998 ). 
Examples of Autoimmune Diseases What is it?
1 . Rheumatoid arthritis
In patients with rheumatoid arthritis , the immune system is significantly perform liningsynovium target damage in the area that encloses joints. Synovial inflammation is usually symmetrical parts ( the same happened congruence of the two organs of the body ), causing pain, swelling, and stiffness in the joints. Rheumatoid arthritis disease is distinguished from the more common osteoarthritis accompanied arthiris case " wear - and- tear " degenerative. Lately focused therapy is done by reducing inflammation of the joints by using anti- inflammatory drugs or immunosuppressive . Sometimes the immune system also damage the lungs, blood vessels or eyes. Rarely appears patients who have symptoms other autoimmune diseases, such as Sjogren 's inflammation, itching and scaly. In some cases oral treatment is often done ( NIH , 1998; Roitt , 1991).
2 . Multiple Sclerosis
Multiple sclerosis is a disease in which the immune system of tissue damage nerve of the central nervous system. Generally, damage to the central nervous system occurs intermittently, allowing the patient to perform normal life activities. At the extreme events, the symptoms so that the patient will seem permanent blindness, paralysis, and premature death. Some sort of drug therapy using interferon beta is very helpful for patients with intermittent symptoms ( NIH, 1998).



Related Articles :

- Huntington Disease
- Lyme Disease
- Drugs and Disease
- Health News
- Healthy Diet
- Healthy Baby